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Systemic lupus erythematosus is a rare autoimmune disease, affecting 15–124 per 100.000 individuals worldwide. The disease is most common in women of child-bearing age and its prevalence decreases with increasing age. Elderly-onset lupus, which is generally defined as lupus first occurring in patients aged 50–65 years, accounts for 10–20% of patients with the disease and is 5-fold more common in women than in men. Changes in cellular immunity and menopause...
